Endocrine Abstracts

Background: T2DM is a metabolic disorder characterized by high blood glucose in the context of insulin resistance and relative insulin deficiency with disturbances of carbohydrate, fat, and protein metabolism.T2DM is a risk factor for Alzheimer’s disease and mild cognitive impairment. The etiology of cognitive impairment in people with T2DM is uncertain, but it is most likely multi factorial. Chronic hyperglycemia, cerebral micro vascular disease, severe hypoglycemia, and...

Background: The term metabolic syndrome refers to a cluster of associated symptoms composed of impaired fasting glucose, abdominal obesity, hypertension, and dyslipidaemia. Metabolic syndrome is associated with an increased risk of cardiovascular and diabetes-associated morbidity and mortality. Further, there is evidence that metabolic syndrome is an effective and simple clinical tool for identifying high-risk subjects predisposed to cardiovascular diseases and diabetes mellit...

Background: Atherosclerotic cardiovascular disease (ASCVD) is a major complication to type 2 diabetes (T2D), in terms of both severity and prevalence rates. The Prevalence and clinical management of the Atherosclerotic Cardiovascular Diseases in patients with Type 2 Diabetes across Middle East and Africa countries (PACT-MEA) is a multinational study that aimed to investigate the prevalence of both established ASCVD and the risk for ASCVD in people with T2D as well as its clini...